Senior Associate Scientist- Bioassay

Job
USA
June 6, 2025

Job Overview

Job Description

We are seeking a highly motivated and passionate Senior Associate Scientist to join our Bioassay Team within the Therapeutic Proteins Department. You will play a critical role in engineering cell lines, developing in vitro cell-based assays, and executing high throughput bioassay screens to identify potential oncology drug candidates.

As a Senior Associate Scientist in the Bioassay Team, a typical day might include:

  • Culturing immortalized cell lines and primary T cells
  • Conducting lentiviral production and transduction of cell lines or primary human T cells to express genes of interest
  • Performing CRISPR gene editing in human cell lines
  • Performing bioassay development and/or optimization in cell lines and/or primary cells (luciferase reporter, viability/cytotoxicity, and/or cytokine release assays)
  • Running high throughput cell-based screens to identify candidate therapeutic antibodies, TCRs, or CARs
  • Conducting cell binding screens via flow cytometry
  • Analyzing data, preparing summaries, and presenting at cross-functional meetings

This role might be for you if you:

  • Are detail-oriented with strong organizational and time-management skills
  • Exhibit flexibility with changing priorities and can effectively manage multiple projects
  • Have excellent verbal and written communication skills

In order to be considered for this role, you must have at least a BS/MS and 3+ years of relevant lab experience. We need someone with a background in immunology; experience with T cell biology and antigen presentation is a plus. Must have experience with therapeutic antibody screening in an industry setting. Experience with in vitro cell-based assay development and engineering mammalian cells is required. Flow cytometry experience including data acquisition and analysis is strongly preferred.

Link: https://careers.regeneron.com/en/jobs/r40056/senior-associate-scientist-bioassay/


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